O51E2_MOUSE Q8VBV9
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UniProt:Q8VBV9
Recommended name：Olfactory receptor 51E2
EC number：
Alternative names：(Olfactory receptor 78)
Cleaved into：
GeneID：170639
Gene names (primary )：Or51e2
Gene names (synonym )：Mol2.3 Olfr78 Psgr
Gene names (ORF )：
Length：320
Mass：35578
Sequence：MSSCNFTHATFLLIGIPGLEEAHFWFGFPLLSMYAVALFGNCIVVFIVRTERSLHAPMYLFLCMLAAIDLALSTSTMPKILALFWFDSREITFDACLAQMFFIHTLSAIESTILLAMAFDRYVAICHPLRHAAVLNNTVTVQIGMVALVRGSLFFFPLPLLIKRLAFCHSNVLSHSYCVHQDVMKLAYTDTLPNVVYGLTAILLVMGVDVMFISLSYFLIIRTVLQLPSKSERAKAFGTCVSHISVVLAFYVPLIGLSVVHRFGNSLDPIVHVLMGDVYLLLPPVINPIIYGAKTKQIRTRVLAMFKISCDKDIEAGGNT
Tissue specificity：In brain, expressed in medulla oblongata by cells close to the fourth ventricle, in the area postrema, the nucleus tractus solitarius (PubMed:11707321). Expressed in olfactory epithelium and vomeronasal organ (PubMed:11069588). Expressed in kidney by large renal vessels, renal afferent arterioles, and extrarenal vascular beds. In small resistance vessels the expression is restricted to cells of the juxtaglomerular afferent arteriole, which mediate renin secretion. Also detected in small blood vessels in a variety of tissues including heart, diaphragm, skeletal muscle, and skin. In the heart, esophagus, and stomach it is detected in axons of autonomic neurons and neurons of the enteric plexus (PubMed:23401498). Also detected in colon and liver (PubMed:23401498). Expressed in the glomus cells of the carotid body (PubMed:26560302). {ECO:0000269|PubMed:11069588, ECO:0000269|PubMed:11707321, ECO:0000269|PubMed:23401498, ECO:0000269|PubMed:26560302}.
Induction：
Developmental stage：Primarily detected between 11 dpc and 12 dpc. Expressed at 12 dpc in the dorsal region of the developing nasal cavity and in the mesenchyme located between the olfactory epithelium and the presumptive olfactory bulb. In the medulla oblongata, first detected at 17 dpc. In the area postrema and the nucleus tractus solitarius expression peaks at P20 and then decreases slightly. {ECO:0000269|PubMed:11069588}.
Protein families：G-protein coupled receptor 1 family