CDK1_RAT P39951
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UniProt:P39951
Recommended name:Cyclin-dependent kinase 1
EC number:EC:2.7.11.22
Alternative names:CDK1
Cleaved into:
GeneID:54237
Gene names (primary ):Cdk1
Gene names (synonym ):Cdc2, Cdc2a, Cdkn1
Gene names (ORF ):
Length:297
Mass:34,135
Sequence:MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM
Tissue specificity:Follow a cyclic expression; during interphase, accumulates gradually following G1, S to reach a critical threshold at the end of G2, which promotes self-activation and triggers onset of mitosis. Induced transiently by TGFB1 at an early phase of TGFB1-mediated apoptosis. Expressed during S-phase in mitogen-stimulated hepatocytes. 2 s
Induction:
Developmental stage:
Protein families: