ALD1_MOUSE P21300
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UniProt:P21300
Recommended name:Aldo-keto reductase family 1 member B7
EC number:EC 1.1.1.21
Alternative names:(Aldehyde reductase) (AR) (Aldose reductase-related protein 1) (MVDP) (Vas deferens androgen-dependent protein)
Cleaved into:
GeneID:11997
Gene names (primary ):Akr1b7
Gene names (synonym ):Avdp
Gene names (ORF ):
Length:316
Mass:35988
Sequence:MATFVELSTKAKMPLVGLGTWKSSPGQVKEAVKAAIDAGYRHIDCAYVYHNENEVGEAIQEKIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLDLYLVHWPQGFQAGNALLPKDNKGKVLLSKSTFLDAWEAMEELVDQGLVKALGISNFNHFQIERLLNKPGLKHKPVTNQIESHPYLTQEKLIQYCQSKGIAVTAYSPLGSPDRPYAKPEDPVVMEIPKIKEIAAKHKKTVAQVLIRFHVQRNVVVIPKSVTPSRIQENLQVFDFQLSEEDMAAILSFNRNWRACDLLDARTEEDYPFHEEY
Tissue specificity:Expressed exclusively in the epithelial cells of the deferent duct. {ECO:0000269|PubMed:1637719}.
Induction:Castration resulted in a marked decrease in the level of the mRNA coding for the protein, whereas administration of testosterone to castrated males resulted in a marked increase. {ECO:0000269|PubMed:2123194}.
Developmental stage:
Protein families:Aldo/keto reductase family