RGN_MOUSE Q64374
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UniProt:Q64374
Recommended name:Regucalcin
EC number:EC 3.1.1.17
Alternative names:(RC) (Gluconolactonase) (GNL) (Senescence marker protein 30) (SMP-30)
Cleaved into:
GeneID:19733
Gene names (primary ):Rgn
Gene names (synonym ):Smp30
Gene names (ORF ):
Length:299
Mass:33407
Sequence:MSSIKVECVLRENYRCGESPVWEEASQSLLFVDIPSKIICRWDTVSNQVQRVAVDAPVSSVALRQLGGYVATIGTKFCALNWENQSVFVLAMVDEDKKNNRFNDGKVDPAGRYFAGTMAEETAPAVLERHQGSLYSLFPDHSVKKYFDQVDISNGLDWSLDHKIFYYIDSLSYTVDAFDYDLQTGQISNRRIVYKMEKDEQIPDGMCIDAEGKLWVACYNGGRVIRLDPETGKRLQTVKLPVDKTTSCCFGGKDYSEMYVTCARDGLNAEGLLRQPDAGNIFKITGLGVKGIAPYSYAG
Tissue specificity:Mainly present in the liver. Weak expression was found in the brain, lung and kidney. {ECO:0000269|PubMed:8765750, ECO:0000269|PubMed:9278263}.
Induction:By calcium. {ECO:0000269|PubMed:9278263}.
Developmental stage:Protein amounts in liver decrease significantly with age.
Protein families:SMP-30/CGR1 family