NRK_MOUSE Q9R0G8
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UniProt:Q9R0G8
Recommended name：Nik-related protein kinase
EC number：EC 2.7.11.1
Alternative names：(Nck-interacting kinase-like embryo specific kinase) (NESK) (NIK-like embryo-specific kinase)
Cleaved into：
GeneID：27206
Gene names (primary )：Nrk
Gene names (synonym )：Nesk
Gene names (ORF )：
Length：1455
Mass：163647
Sequence：MAGPGSWRDKEVTDLGQLPDPTGIFSLDKAIGLGTYGRIFLGIHEKTGSLVAVKVMSARKTPLPEIGRRVRVNKYQKSVGWRYSDEEEDLRTELNLLRKYSFHKNIVTFYGAFFKLNPPGHQHQLWMVMELCAAGSVTDVVRMTRNQSLKEDWIAYICREILQGLAHLHAHQVIHRDIKGQNVLLTHDAEVKIVDFGVSAQVSRTNGRRNSFIGTPYWMAPEVIHCDEDPRCSYDYRSDVWSVGITAIEMAEGAPPLCKLQPLEALCVILREAAPKVKSSGWSRKFQNFMENCMIKNFLFRPTSGNMLLHPFVHDIKNERRVVESLTKHLTGIIQKREKKGIPVAFEGEEAAKEQYITRRFRGPSCTPELLRVPTSSRCRPLRVLHGEPPQPRWLPDQEDPQDQELQQLQKAAGVFMPLHSQDNTSKLFPKQVEVAPYLRGAAQVVMPVLVQVEAPPQVSKAAQMLKSLPTQDNKATSPEVQAPVAEGQQAQHEALETEQPKDLDQVPEEFQGQDRAPEQPRQGQAAEQQQIHNPVPEQPPEEDREPEQAEVQEEAVEPPQAEIEDKEPEVVQVHAQVLLPLLSQNRHVLLPLHLDRQLLIPVGEQNEEVPRAQAWDLEASRAVGAVQALIEGLSRDLLRAPNAFVTKPLGPLQIFLENLSTDGFYTEPEPTQKKKSKVASLRKAIAKRLRPKRFRAKALWRLEDFEFSDVETSRRRRHRRWEDIFNQHEEQLRRVENDREDDSSDNDEVFHSIQAEVQIEPHAANPAGNEVHERSAPMPCNRNRTHRVKFSPSVGEEEPSLEEAQPQQQQQQPMNIRPRNCLNPQNFQAQSDSSSEEDSPVTRRKSQSSPPYSTIDQKLLIDIHVPDGFKVGKISPPVYLTNEWVGYNALSEIFWDDWIMPTRPARPPEEDGDYVELYDADANANGDEEVANGAYEDPRDGANGHDDMNNQLDQANGYEGHGAAGYNGGDVGGNHGAAFNGPRANYPRAGILKNGHNDGRALNRGAFGVFGDNAARAFHGAAGEAGAAFGNHGANRGNGRGNRNREANGRNEENGAFGRDQHVFPEFEHEESDRGTETSDSIALEITSFDGEQNSGRPVSSTTMGFPIGRSSPRGSDFGSDISYNSPILHVYEKDFSSEVYCGSLWGVNLLLGTQSHLYLMDRSGKAEIVKLIKRRPFRQIQVVEQLNLLITISGKKNRLRVYHLSWLRNKILNNDPKSKKRQKAMRKKEEACKAIDKLIGCEHFSVLQHEETTYIAVAVKSSIHLFAWAPKSFDENTAIKVFPTRDLKPLTVDLAVGSEKTLKIFFSSANGYHIIDAESEVMSEVTLPNNNVVILPDCLGLGVMLSLNAEAASEEANEQLLKKILDVWKDIPSSVAFECTKRITGWDQKAIEVRSLQSTILENELKRRSIKKLRFLCARGDKMFFASTLSNDHSRVYLMSLGKLEELHRSYAV
Tissue specificity：
Induction：
Developmental stage：Predominantly expressed in skeletal muscle during embryogenesis. Expression was detected in the myotome at 10.5 dpc and, thereafter, was observed in developing skeletal musculature from 11.5 to 13.5 dpc and increased from 15 to 17 dpc. However, expression in skeletal muscle was not observed in adults. Its expression may be down-regulated as development proceeds. {ECO:0000269|PubMed:10559491, ECO:0000269|PubMed:10801798, ECO:0000269|PubMed:12837278}.
Protein families：Protein kinase superfamily, STE Ser/Thr protein kinase family, STE20 subfamily