ACOT1_MOUSE O55137
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UniProt:O55137
Recommended name:Acyl-coenzyme A thioesterase 1
EC number:EC 3.1.2.-
Alternative names:(Acyl-CoA thioesterase 1) (CTE-I) (Inducible cytosolic acyl-coenzyme A thioester hydrolase) (Long chain acyl-CoA thioester hydrolase) (Long chain acyl-CoA hydrolase) (Palmitoyl-coenzyme A thioesterase) (EC 3.1.2.2)
Cleaved into:
GeneID:26897
Gene names (primary ):Acot1
Gene names (synonym ):Cte1
Gene names (ORF ):
Length:419
Mass:46136
Sequence:MEATLNLEPSGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLVKRDVQTPFVVELEVLDGHEPDGGQRLAHAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKNMETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKGITAAVVINGSVAAVGNTISYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPLVDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHAMAQLDAWQQLQTFFHKQLGSECLHVSPKI
Tissue specificity:Expressed in heart, kidney, brown adipose tissue, white adipose tissue, adrenal gland and muscle. {ECO:0000269|PubMed:10567408, ECO:0000269|PubMed:11330065}.
Induction:In the liver, by peroxisome proliferator (Clofibrate) treatment, via the peroxisome proliferator-activated receptors (PPARs) or fasting for 24 hours. {ECO:0000269|PubMed:11330065}.
Developmental stage:
Protein families:C/M/P thioester hydrolase family