ATAT_MOUSE Q8K341
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UniProt:Q8K341
Recommended name:Alpha-tubulin N-acetyltransferase 1
EC number:EC 2.3.1.108
Alternative names:(Alpha-TAT) (Alpha-TAT1) (TAT) (Acetyltransferase mec-17 homolog)
Cleaved into:
GeneID:73242
Gene names (primary ):Atat1
Gene names (synonym ):Mec17
Gene names (ORF ):
Length:421
Mass:47164
Sequence:MEFPFDVDALFPERITVLDQHLRPPARRPGTTTPARVDLQQQIMTIVDELGKASAKAQHLPAPITSALRMQSNRHVIYILKDTSARPAGKGAIIGFLKVGYKKLFVLDDREAHNEVEPLCILDFYIHESVQRHGHGRELFQHMLQKERVEPHQLAIDRPSPKLLKFLNKHYNLETTVPQVNNFVIFEGFFAHQHRPPTSSLRATRHSRAAVADPIPAAPARKLPPKRAEGDIKPYSSSDREFLKVAVEPPWPLNRAPRRATPPAHPPPRSSSLGNSPDRGPLRPFVPEQELLRSLRLCPPHPTARLLLATDPGGSPAQRRRTRGTPWGLVAQSCHYSRHGGFNTSFLGTGNQERKQGEQEAEDRSASEDRVLLLDGSGEEPTQTGAPRAQAPPPQSWTVGGDIMNARVIRNLQERRSTRPW
Tissue specificity:Widely expressed with highest levels in neuronal tissues. In the brain, expressed in the cortex, cerebellum and hippocampus, including the pyramidal layers in CA1 and CA3, as well as the granular cell layers in the lateral blade (suprapyramidal portion) and the medial blade (infrapyramidal portion) of the dentate gyrus. In testis, mainly expressed in the internal cell layers of seminiferous tubules, where spermatocytes and spermatids are located. {ECO:0000269|PubMed:23275437, ECO:0000269|PubMed:23720746}.
Induction:
Developmental stage:Widely expressed in embryos during development with particularly high expression in the spinal cord at 13.5 dpc. {ECO:0000269|PubMed:23720746}.
Protein families:Acetyltransferase ATAT1 family