S38A2_RAT Q9JHE5
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UniProt:Q9JHE5
Recommended name：Sodium-coupled neutral amino acid symporter 2
EC number：
Alternative names：
Cleaved into：
GeneID：29642
Gene names (primary )：Slc38a2
Gene names (synonym )：Ata2 1 Publication, Sa1 1 Publication, Sat2 1 Publication, Snat2 1 Publication
Gene names (ORF )：
Length：504
Mass：55,554
Sequence：MKKTEMGRFNISPDEDSSSYSSNGDFNYSYPTKQAALKSHYVDVDPENQNFLLESNLGKKKYETDFHPGTTSFGMSVFNLSNAIVGSGILGLSYAMANTGIALFIILLTFVSIFSLYSVHLLLKTANEGGSLLYEQLGHKAYGLAGKLAASGSITMQNIGAMSSYLFIVKYELPLVIKALMNIEDTNGLWYLNGDYLVLLVSFVLILPLSLLRNLGYLGYTSGLSLLCMIFFLIVVICKKFQIPCPVEVALMANETVNGTFTQVALAALASNSTAADTCRPRYFIFNSQTVYAVPILTFSFVCHPAVLPIYEELKSRSRRRMMNVSKISFFAMFLMYLLAALFGYLTFYEHVESELLHTYSAIVGTDILLLVVRLAVLVAVTLTVPVVIFPIRSSVTHLLCPTKEFSWFRHSVITVTILAFTNLLVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKEPMRSVQKIGALCFLLSGVVVMIGSMGLIVLDWVHDASAGGH
Tissue specificity：Widely expressed (PubMed:10747860, PubMed:10811809, PubMed:10859363). Expressed in skeletal muscle and adipose tissue (at protein level) (PubMed:11311116, PubMed:15561425). Expressed by glutamatergic and GABAergic neurons together with astrocytes and other non-neuronal cells in the cerebral cortex (at protein level) (PubMed:15561425, PubMed:16616430, PubMed:18832333). Widely expressed in the central nervous systeme where, it is enriched in the spinal cord and the brainstem nuclei, especially those of the auditory system (PubMed:15561425). 7 s
Induction：
Developmental stage：Up-regulation upon amino acid deprivation results from both increased transcription and protein stabilization (PubMed:11311116, PubMed:17488712, PubMed:18330498). Up-regulated by TGFB1 (PubMed:11716780). Up-regulation by insulin and osmotic shock (PubMed:18330498). 4 s
Protein families：amino acid/polyamine transporter 2 family