SPAT6_MOUSE Q3U6K5
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UniProt:Q3U6K5
Recommended name：Spermatogenesis-associated protein 6
EC number：
Alternative names：(Kinesin-related protein)
Cleaved into：
GeneID：67946
Gene names (primary )：Spata6
Gene names (synonym )：Hash
Gene names (ORF )：
Length：488
Mass：56101
Sequence：MPKVKALQCALALEIRSVTCPGVVLKDKEDIYLSICVFGQYKKTQCVPATFPLVFNARMVFEKVFPEAVDPGDVVAQLEYDTAVFELIQLVPPVGETLSTYDENTRDFMFPGPNQMSGHHDSNRQVTMRRISGLRGIAPKLEFSTTSVITECLISSRKCRTQDKFTYHSAPVEKSHGRLQCRTSRSQKKKSKSPERSKYCINTKNYEQPTISSKSHSPSPYTKRRMCELSEDTRRRLAHLNLGPYEFKKETDKPPFVIRHVDPPSPRTDNFFGSPGRDCERDGWVRMHSDHPHIGCCRSKDYKVIRSPHGRDFEDPFERCEEYLSPRTCSKPQHSARTLLVHSAPSTTPKHCASPVLNRASLRERFHSDWCSPPNCDEIHDRVKDVLKSHQAHARHLCDERDPEREDELELKRSLLYRDSAYDSDPEYSSFQRPRGSFHLDDGECWSNRAASCKGKSHRPVFENSMDKMYRNLYKKACSSVSHTQESF
Tissue specificity：Specifically expressed in developing spermatids and mature spermatozoa (at protein level) (PubMed:25605924). Isoform 1 is weakly expressed in testis, ovary, thymus and placenta. Isoform 2 and isoform 3 are testis-specific. Expression isw higher in spermatids than in spermatocytes and spermatogonia (PubMed:12771232). {ECO:0000269|PubMed:12771232, ECO:0000269|PubMed:25605924}.
Induction：
Developmental stage：Weak expression of isoform 1 is seen throughout testicular development. Isoform 2 and isoform 3 could not be detected until postnatal day 15. Expressed from postnatal day 20, and thereafter increased. Expressed in blastocysts and in embryos from 8.5 dpc-12.5 dpc. After 13.5 dpc, the level of expression decreases. Expressed at 9.5-10.5 dpc in the neural tube, in somites and limb buds. {ECO:0000269|PubMed:12771232}.
Protein families：SPATA6 family