ARI2_HUMAN O95376
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UniProt:O95376
Recommended name：E3 ubiquitin-protein ligase ARIH2
EC number：EC:2.3.2.31
Alternative names：(ARI-2) (Protein ariadne-2 homolog) (RING-type E3 ubiquitin transferase ARIH2) (Triad1 protein)
Cleaved into：
GeneID：10425
Gene names (primary )：ARIH2
Gene names (synonym )：ARI2 TRIAD1
Gene names (ORF )：HT005
Length：493
Mass：57819
Sequence：MSVDMNSQGSDSNEEDYDPNCEEEEEEEEDDPGDIEDYYVGVASDVEQQGADAFDPEEYQFTCLTYKESEGALNEHMTSLASVLKVSHSVAKLILVNFHWQVSEILDRYKSNSAQLLVEARVQPNPSKHVPTSHPPHHCAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVFPLLPNEELREKYRRYLFRDYVESHYQLQLCPGADCPMVIRVQEPRARRVQCNRCNEVFCFKCRQMYHAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSKCKHDFCWMCLGDWKTHGSEYYECSRYKENPDIVNQSQQAQAREALKKYLFYFERWENHNKSLQLEAQTYQRIHEKIQERVMNNLGTWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVERADSYDRGDLENQMHIAEQRRRTLLKDFHDT
Tissue specificity：Widely expressed with higher expression in granulocytes. {ECO:0000269|PubMed:16118314}.
Induction：Up-regulated by all-trans retinoic acid (ATRA). Up-regulated during differentiation of immature blood cells toward monocytes and granulocytes. {ECO:0000269|PubMed:16118314}.
Developmental stage：
Protein families：RBR family, Ariadne subfamily