PDGFD_RAT Q9EQT1
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UniProt:Q9EQT1
Recommended name:Platelet-derived growth factor D
EC number:
Alternative names:Iris-expressed growth factor Spinal cord-derived growth factor B (SCDGF-B)
Cleaved into:
GeneID:
Gene names (primary ):Pdgfd
Gene names (synonym ):Iegf, Scdgfb
Gene names (ORF ):
Length:370
Mass:42,809
Sequence:MHRLILVSILVCANFCCYRDTFATPQSASIKALRNANLRRDESNHLTDLYRRDENIRVTGTGHVQSPRFPNSYPRNLLLTWRLHSQEKTRIQLAFDHQFGLEEAENDICRYDFVEVEDVSESSTVVRGRWCGHKEIPPRITSRTNQIKITFQSDDYFVAKPGFKIYYSFVEDFQPEAASEINWESVTSSFSGVSYHSPSVMDSTLTADALDKAIAEFDTVEDLLKYFNPASWQDDLENLYMDTPRYRGRSYHERKSKVDLDRLNDDVKRYSCTPRNHSVNLREELKLTNAVFFPRCLLVQRCGGNCGCGTLNWKSCTCSSGKTVKKYHEVLKFEPGHFKRRGKAKNMALVDIQLDHHERCDCICSSRPPR
Tissue specificity:Widely expressed. Expressed at high levels in the kidney, adrenal glands, eye and CNS. In the kidney the localization is confined to arterial and arteriolar vascular smooth muscle cells and is also detected at low levels in the glomeruli In the eye in the anterior segment it is localized to the iris and ciliary body. In the retina localizes intensely to the outer plexiform layer, which contains photoreceptor axons and the synaptic layer between photoreceptors and second order neurons. In the spinal cord, prominently expressed in the motorneurons. 3 s
Induction:
Developmental stage:Not detected in the spinal cord at 21 dpc. Expressed weakly at postnatal day 1 (P1) and a strong expression seen at P21 and this continues into adulthood. 1
Protein families: