PSB5_HUMAN P28074
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UniProt:P28074
Recommended name:Proteasome subunit beta type-5
EC number:EC:3.4.25.1
Alternative names:(Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)
Cleaved into:
GeneID:5693
Gene names (primary ):PSMB5
Gene names (synonym ):LMPX MB1 X
Gene names (ORF ):
Length:263
Mass:28480
Sequence:MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP
Tissue specificity:
Induction:Down-regulated by IFNG/IFN-gamma (at protein level). Induced in breast cancer tissue. Up-regulated by sulforaphane in breast cancer cells. {ECO:0000269|PubMed:17004105, ECO:0000269|PubMed:18602823, ECO:0000269|PubMed:8066462, ECO:0000269|PubMed:8663318}.
Developmental stage:
Protein families:Peptidase T1B family