B3GL1_MOUSE Q920V1
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UniProt:Q920V1
Recommended name:UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1
EC number:EC 2.4.1.79
Alternative names:(Beta-1,3-GalNAc-T1) (Beta-1,3-galactosyltransferase 3) (Beta-1,3-GalTase 3) (Beta3Gal-T3) (Beta3GalT3) (b3Gal-T3) (Beta-3-Gx-T3) (Brainiac 1) (Galactosylgalactosylglucosylceramide beta-D-acetyl-galactosaminyltransferase) (Globoside synthase) (UDP-N-acetylgalactosamine:globotriaosylceramide beta-1,3-N-acetylgalactosaminyltransferase)
Cleaved into:
GeneID:26879
Gene names (primary ):B3galnt1
Gene names (synonym ):B3galt3 B3gt3 Mbrn1
Gene names (ORF ):
Length:331
Mass:39371
Sequence:MAPAVLTALPNRMSLRSLKWSLLLLSLLSFLVIWYLSLPHYNVIERVNWMYFYEYEPIYRQDFRFTLREHSNCSHQNPFLVILVTSRPSDVKARQAIRVTWGEKKSWWGYEVLTFFLLGQQAEREDKTLALSLEDEHVLYGDIIRQDFLDTYNNLTLKTIMAFRWVMEFCPNAKYIMKTDTDVFINTGNLVKYLLNLNHSEKFFTGYPLIDNYSYRGFFHKNHISYQEYPFKVFPPYCSGLGYIMSGDLVPRVYEMMSHVKPIKFEDVYVGICLNLLKVDIHIPEDTNLFFLYRIHLDVCQLRRVIAAHGFSSKEIITFWQVMLRNTTCHY
Tissue specificity:Detected in brain, ovary, kidney, uterus and stomach (PubMed:9417047, PubMed:11463849). In ovary, specifically expressed in follicular granulosa cells and shows particularly strong expression at later stages of follicle development (PubMed:11463849). {ECO:0000269|PubMed:11463849, ECO:0000269|PubMed:9417047}.
Induction:
Developmental stage:Detected in embryos from 12.5 days post coitum (dpc) onwards. Expressed in all four ventricles of the developing brain, with highest expression in the outer ventricular layer. Also found in the limb buds at 12.5 dpc. Detected in the brain (hippocampus) and retina at postnatal day 1. Expression in the retina is localized to the ganglion cell layer. At postnatal day 10, expression remains strong in the hippocampus where it localizes to the four CA fields and the dentate gyrus. {ECO:0000269|PubMed:11463849}.
Protein families:Glycosyltransferase 31 family