KAPCA_HUMAN P17612
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UniProt:P17612
Recommended name:cAMP-dependent protein kinase catalytic subunit alpha
EC number:EC:2.7.11.11
Alternative names:(PKA C-alpha)
Cleaved into:
GeneID:5566
Gene names (primary ):PRKACA
Gene names (synonym ):PKACA
Gene names (ORF ):
Length:351
Mass:40590
Sequence:MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
Tissue specificity:Isoform 1 is ubiquitous. Isoform 2 is sperm-specific and is enriched in pachytene spermatocytes but is not detected in round spermatids. {ECO:0000269|PubMed:10906071, ECO:0000269|PubMed:21812984}.
Induction:
Developmental stage:
Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily