NENF_HUMAN Q9UMX5
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UniProt:Q9UMX5
Recommended name:Neudesin
EC number:
Alternative names:(Cell immortalization-related protein 2) (Neuron-derived neurotrophic factor) (Protein GIG47) (Secreted protein of unknown function) (SPUF protein)
Cleaved into:
GeneID:29937
Gene names (primary ):NENF
Gene names (synonym ):CIR2 SPUF
Gene names (ORF ):
Length:172
Mass:18856
Sequence:MVGPAPRRRLRPLAALALVLALAPGLPTARAGQTPRPAERGPPVRLFTEEELARYGGEEEDQPIYLAVKGVVFDVTSGKEFYGRGAPYNALTGKDSTRGVAKMSLDPADLTHDTTGLTAKELEALDEVFTKVYKAKYPIVGYTARRILNEDGSPNLDFKPEDQPHFDIKDEF
Tissue specificity:Ubiquitously expressed with high expression in heart. Over-expressed in various tumors including carcinomas of the uterine cervix, lymphoma, colon, lung, skin and leukemia, as well as carcinoma of the breast. {ECO:0000269|PubMed:22748190}.
Induction:Up-regulated in immortal cells. Induced in estrogen receptor positive breast cancer expressing progesterone receptor. {ECO:0000269|PubMed:16645950, ECO:0000269|PubMed:9771976}.
Developmental stage:
Protein families:Cytochrome b5 family, MAPR subfamily