MESP1_MOUSE P97309
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UniProt:P97309
Recommended name：Mesoderm posterior protein 1
EC number：
Alternative names：
Cleaved into：
GeneID：17292
Gene names (primary )：Mesp1
Gene names (synonym )：
Gene names (ORF )：
Length：243
Mass：26386
Sequence：MAQPLCEPRSESWILSPAGRQPPMPSDGNSVCSPAWSSDPWDGAQASSPAPPCARPARRAGTPGRRGTHGSRLGSGQRQSASEREKLRMRTLARALHELRRFLPPSVAPTGQNLTKIETLRLAIRYIGHLSAVLGLSEDNLRRQRHAVSPRGCPLCPDSDLAQSQSLGPRLSPAVCSGVSWGSPPAYPRPRVAAESWDPSFLYAETASQERQEMEPSPSSPLFSSDMLALLETWTPPQEWPPA
Tissue specificity：No expression was detected in adult tissues except the testis. Expression in the testis was regulated developmentally; expressed 2 weeks after birth, and increases, reaching the full expression level in mature testes. {ECO:0000269|PubMed:8787751}.
Induction：Expression is induced by Notch signaling.
Developmental stage：The earliest expression is detected at the junction of the epiblast and extraembryonic ectoderm, which is the initiation site for gastrulation. Around 6.5-6.75 dpc, expression becomes evident as gastrulation progresses. Expression does not spread over all mesodermal cells; it is seen only in a fraction of cells, particularly those in the early emergence group destined to become the extraembryonic mesoderm and the most posterior part of the tailbud. Expression remains for a while at the base of the allantois, and then spreads out to the lateral margins of the tail bud mesoderm. Expressed in the anterior presomitic mesoderm in a broad or thin stripe pattern. Expressed in the paraxial mesoderm during somitogenesis. Expression disappears before 8.5 dpc. {ECO:0000269|PubMed:10887078, ECO:0000269|PubMed:15677726, ECO:0000269|PubMed:17306789, ECO:0000269|PubMed:8787751}.
Protein families：