CLD2_MOUSE O88552
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UniProt:O88552
Recommended name:Claudin-2
EC number:
Alternative names:
Cleaved into:
GeneID:12738
Gene names (primary ):Cldn2
Gene names (synonym ):
Gene names (ORF ):
Length:230
Mass:24484
Sequence:MASLGVQLVGYILGLLGLLGTSIAMLLPNWRTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAMSSLACIISVVGMRCTVFCQDSRAKDRVAVVGGVFFILGGILGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISALFSLVAGVILCFSCSPQGNRTNYYDGYQAQPLATRSSPRSAQQPKAKSEFNSYSLTGYV
Tissue specificity:Expressed in the kidney, liver and intestine, with higher levels in the ileum than in the jejunum. Low levels in the brain. {ECO:0000269|PubMed:11934881, ECO:0000269|PubMed:9647647}.
Induction:By CDX1 and CDX2. Induction by CDX2, but not CDX1, is potentiated by TCF1. {ECO:0000269|PubMed:11934881}.
Developmental stage:
Protein families:Claudin family