KAPCA_MOUSE   P05132


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UniProt:P05132

Recommended name:cAMP-dependent protein kinase catalytic subunit alpha

EC number:EC 2.7.11.11

Alternative names:(PKA C-alpha) (EC 2.7.11.11)

Cleaved into:

GeneID:18747

Gene names  (primary ):Prkaca

Gene names  (synonym ):Pkaca

Gene names  (ORF ):

Length:351

Mass:40571

Sequence:MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVMLVKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF

Tissue specificity:Isoform 2 is sperm specific.

Induction:

Developmental stage:Accumulates in oocytes before fertilization but fades out after fertilization. {ECO:0000269|PubMed:18367160}.

Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily


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