TGM4_RAT   Q99041


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UniProt:Q99041

Recommended name:Protein-glutamine gamma-glutamyltransferase 4

EC number:EC:2.3.2.13

Alternative names:Dorsal prostate transglutaminase Dorsal protein 1 (DP1) Transglutaminase-4 (TGase-4)

Cleaved into:

GeneID:64679

Gene names  (primary ):Tgm4

Gene names  (synonym ):Dp1

Gene names  (ORF ):

Length:667

Mass:75,587

Sequence:MDSRNMLVVYSVNLEKKLNAAAHHTIEYQTQKLVLRRGQIFSLKVMLNRPLQSHDELKLIFNTGHNMPFYTVELDPMTSYRSKGWQVKIAKQSGVEVVLNVISAADAVVGRYTMNVNEFDAGVFFLLFNPWCSDDSVFMASEEDRAEYVLNDTGYMYMGFAKQIKEKPWTFGQFEKYILNCCFRLLTHLEPKEMQSPVLVSRAICTMMCAANNFGVLVGNWTGDYSNGTAPYVWASSVPILQQHYITRMPVRFGQCWVFSGVLTTALRAVGIPARSVTNFESAHDTEKNLRVDIYLDESGKTIPHLTKDSVWNFHMWTDAWMKRQDLPQGHDGWQVLDSTPQEISEGQFRIGPSPVSAIRQGLVQIMYDTTFVFTEVNGDKYIWLVKQNQEREKNVLIAVETASIGKNISTKMVGENRRQDITLHYKFPEGSPEERKAMEKASGKRPDDKLNSRTLHISVLQNSVELGHPINLTIVLKRKTATPQNVNISCSLDLQTYTGNKKTNLGVIQKTVQIQGQESEVSLSMDSSFYIYKLGMVDDEMVIKGFIIAEIVDSGERVATDTTLCFLYSAFSVEMPSTSKVNQPLTITCNFKNTLPIPLTNIKFSVESLGLNNMKSWEQETVPPGKTINFQIECTPVKTGPRKFIVKFISRQVKEVHAEKVVLITK

Tissue specificity:Expressed in the coagulating gland, the dorsal part of the prostate and in semen (at protein level). Expressed at low levels in the lateral prostate and seminal vesicle. Not expressed in the epididymis, kidney, liver, serum, sperm plug, testes and ventral prostate. 2 s

Induction:

Developmental stage:Androgen dependent, as shown by the decrease in the level of the protein following castration. 2 s

Protein families:


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