FGFP1_HUMAN   Q14512


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UniProt:Q14512

Recommended name:Fibroblast growth factor-binding protein 1

EC number:

Alternative names:(FGF-BP) (FGF-BP1) (FGF-binding protein 1) (FGFBP-1) (17 kDa heparin-binding growth factor-binding protein) (17 kDa HBGF-binding protein) (HBp17)

Cleaved into:

GeneID:9982

Gene names  (primary ):FGFBP1

Gene names  (synonym ):FGFBP HBP17

Gene names  (ORF ):

Length:234

Mass:26264

Sequence:MKICSLTLLSFLLLAAQVLLVEGKKKVKNGLHSKVVSEQKDTLGNTQIKQKSRPGNKGKFVTKDQANCRWAATEQEEGISLKVECTQLDHEFSCVFAGNPTSCLKLKDERVYWKQVARNLRSQKDICRYSKTAVKTRVCRKDFPESSLKLVSSTLFGNTKPRKEKTEMSPREHIKGKETTPSSLAVTQTMATKAPECVEDPDMANQRKTALEFCGETWSSLCTFFLSIVQDTSC

Tissue specificity:Expressed in the suprabasal region of the epidermis, in hair follicles, the basement membrane at the dermo-epidermal junction (occasionally extending into the basement membrane of dermal blood vessels), wounded skin and several invasive squamous cell carcinomas (at protein level). Expressed in normal and wounded skin and various squamous cell carcinomas. {ECO:0000269|PubMed:11148217, ECO:0000269|PubMed:15806171, ECO:0000269|PubMed:1885605}.

Induction:Up-regulated in epithelial cells after skin injury. Keratinocyte mitogens. {ECO:0000269|PubMed:15806171}.

Developmental stage:

Protein families:Fibroblast growth factor-binding protein family


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