HEPS_HUMAN   P05981


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UniProt:P05981

Recommended name:Serine protease hepsin

EC number:EC:3.4.21.106

Alternative names:(Transmembrane protease serine 1)

Cleaved into:Serine protease hepsin non-catalytic chain; Serine protease hepsin catalytic chain

GeneID:3249

Gene names  (primary ):HPN

Gene names  (synonym ):TMPRSS1

Gene names  (ORF ):

Length:417

Mass:45011

Sequence:MAQKEGGRTVPCCSRPKVAALTAGTLLLLTAIGAASWAIVAVLLRSDQEPLYPVQVSSADARLMVFDKTEGTWRLLCSSRSNARVAGLSCEEMGFLRALTHSELDVRTAGANGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCGRRKLPVDRIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVTQL

Tissue specificity:Detected in liver and kidney. {ECO:0000269|PubMed:21875933}.

Induction:

Developmental stage:

Protein families:Peptidase S1 family


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