F16P1_MOUSE Q9QXD6
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UniProt:Q9QXD6
Recommended name：Fructose-1,6-bisphosphatase 1
EC number：EC 3.1.3.11
Alternative names：(FBPase 1) (D-fructose-1,6-bisphosphate 1-phosphohydrolase 1) (Fructose-1,6-bisphosphatase isozyme 3) (FBPase 3) (Liver FBPase)
Cleaved into：
GeneID：14121
Gene names (primary )：Fbp1
Gene names (synonym )：Fbp Fbp3
Gene names (ORF )：
Length：338
Mass：36912
Sequence：MANHAPFETDISTLTRFVMEQGRKAQGTGELTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGSTNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEENTNAIIIEPEKRGKYVVCFDPLDGSSNIDCLVSIGTIFGIYRKKSTDEPSEKDALQPGRDLVAAGYALYGSATMLVLAMDCGVNCFMLDPSIGEFIMVDRDVKMKKKGNIYSLNEGYAKDFDPAINEYLQRKKFPPDGSAPYGARYVGSMVADIHRTLVYGGIFLYPANKKSPSGKLRLLYECNPIAYVMEKAGGLATTGDKDILDIVPTEIHQKAPVVMGSSEDVQEFLEIYRKHKAK
Tissue specificity：Detected in pancreatic beta-cell lines MIN6 and beta-TC and in liver (at protein level). Preferentially expressed in liver, with lower levels detected in pancreatic islets and intestine, and very low levels in blood, muscle, brain and spleen. {ECO:0000269|PubMed:11250076, ECO:0000269|PubMed:16497803, ECO:0000269|PubMed:18375435, ECO:0000269|PubMed:20719858}.
Induction：Up-regulated in pancreas by obesity and dietary fat intake and in diabetic animals. {ECO:0000269|PubMed:18375435}.
Developmental stage：
Protein families：FBPase class 1 family