TRXR2_HUMAN Q9NNW7
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UniProt:Q9NNW7
Recommended name：Thioredoxin reductase 2, mitochondrial
EC number：EC:1.8.1.9
Alternative names：(Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3)
Cleaved into：
GeneID：10587
Gene names (primary )：TXNRD2
Gene names (synonym )：KIAA1652 TRXR2
Gene names (ORF )：
Length：524
Mass：56507
Sequence：MAAMAVALRGLGGRFRWRTQAVAGGVRGAARGAAAGQRDYDLLVVGGGSGGLACAKEAAQLGRKVAVVDYVEPSPQGTRWGLGGTCVNVGCIPKKLMHQAALLGGLIQDAPNYGWEVAQPVPHDWRKMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVCGVAKGGKEILLSADHIIIATGGRPRYPTHIEGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTIMMRSIPLRGFDQQMSSMVIEHMASHGTRFLRGCAPSRVRRLPDGQLQVTWEDSTTGKEDTGTFDTVLWAIGRVPDTRSLNLEKAGVDTSPDTQKILVDSREATSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCVGLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGPNAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSGLDPTVTGCUG
Tissue specificity：Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690). {ECO:0000269|PubMed:10215850, ECO:0000269|PubMed:10608886, ECO:0000269|PubMed:24601690, ECO:0000269|PubMed:9923614}.
Induction：
Developmental stage：
Protein families：Class-I pyridine nucleotide-disulfide oxidoreductase family