PSA3_HUMAN   P25788


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UniProt:P25788

Recommended name:Proteasome subunit alpha type-3

EC number:

Alternative names:(Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)

Cleaved into:

GeneID:5684

Gene names  (primary ):PSMA3

Gene names  (synonym ):HC8 PSC8

Gene names  (ORF ):

Length:255

Mass:28433

Sequence:MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM

Tissue specificity:

Induction:Down-regulated by antioxidants BO-653 and probucol. Up-regulated by bacterial lipopolysaccharides (LPS) and TNF. {ECO:0000269|PubMed:11521686, ECO:0000269|PubMed:12472671, ECO:0000269|PubMed:16298756}.

Developmental stage:

Protein families:Peptidase T1A family


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