PSA3_HUMAN P25788
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UniProt:P25788
Recommended name:Proteasome subunit alpha type-3
EC number:
Alternative names:(Macropain subunit C8) (Multicatalytic endopeptidase complex subunit C8) (Proteasome component C8)
Cleaved into:
GeneID:5684
Gene names (primary ):PSMA3
Gene names (synonym ):HC8 PSC8
Gene names (ORF ):
Length:255
Mass:28433
Sequence:MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM
Tissue specificity:
Induction:Down-regulated by antioxidants BO-653 and probucol. Up-regulated by bacterial lipopolysaccharides (LPS) and TNF. {ECO:0000269|PubMed:11521686, ECO:0000269|PubMed:12472671, ECO:0000269|PubMed:16298756}.
Developmental stage:
Protein families:Peptidase T1A family