PORED_HUMAN   Q9H8P0


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UniProt:Q9H8P0

Recommended name:Polyprenol reductase

EC number:EC:1.3.1.94

Alternative names:(3-oxo-5-alpha-steroid 4-dehydrogenase 3) (Steroid 5-alpha-reductase 2-like) (Steroid 5-alpha-reductase 3) (S5AR 3) (SR type 3)

Cleaved into:

GeneID:79644

Gene names  (primary ):SRD5A3

Gene names  (synonym ):SRD5A2L

Gene names  (ORF ):

Length:318

Mass:36521

Sequence:MAPWAEAEHSALNPLRAVWLTLTAAFLLTLLLQLLPPGLLPGCAIFQDLIRYGKTKCGEPSRPAACRAFDVPKRYFSHFYIISVLWNGFLLWCLTQSLFLGAPFPSWLHGLLRILGAAQFQGGELALSAFLVLVFLWLHSLRRLFECLYVSVFSNVMIHVVQYCFGLVYYVLVGLTVLSQVPMDGRNAYITGKNLLMQARWFHILGMMMFIWSSAHQYKCHVILGNLRKNKAGVVIHCNHRIPFGDWFEYVSSPNYLAELMIYVSMAVTFGFHNLTWWLVVTNVFFNQALSAFLSHQFYKSKFVSYPKHRKAFLPFLF

Tissue specificity:Expressed in preadipocytes (at protein level) (PubMed:26855069). Overexpressed in hormone-refractory prostate cancers (HRPC). Almost no or little expression in normal adult organs. {ECO:0000269|PubMed:17986282, ECO:0000269|PubMed:26855069}.

Induction:

Developmental stage:

Protein families:Steroid 5-alpha reductase family, Polyprenol reductase subfamily


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