AHI1_MOUSE   Q8K3E5


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UniProt:Q8K3E5

Recommended name:Jouberin

EC number:

Alternative names:(Abelson helper integration site 1 protein) (AHI-1)

Cleaved into:

GeneID:

Gene names  (primary ):Ahi1

Gene names  (synonym ):

Gene names  (ORF ):

Length:1047

Mass:119650

Sequence:MEPETPEKVDSAQEKVRGKTPTADDSDDSREKTGIEEKGELTDAYQLQVAEEMAKEIKKKIRKKLKEQLTYFPPDTLLHDDKLASEKRKKKKKKVPVPTKPESSPSDVCDSAVEGEQKKEGTPEDSQHMEGICSREQDVDATVPENAKPKPKKTKKKTKAVSNDNEDTNGDGVHEITSRDSPVHPKCLLDDDLVMGVYIHRTDRLKSDFMISHPMVKIHVVDEHTGQYVKKDDSERPVSSYYEKDNVDYILPIMTQPYDFKKLKSRLPEWEEQVIFNENFPYLLREFEECPKVILFFEILDFLSMDEIKNNSEVQNQECGFRKIAWAFLKLLGANGNANINSKLRLQLYYPPTKPRSQLNVVEVFEWWSKCPRNRYPSTLYVTVRGLKVPDCIKPSYRSMMALQEERGTPVYCERHRETSSVDTEPGLEDSKEEVKWKRLPGQACRIPNKHLFSLNAGERGCFCLDFSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLDWSKDDRYLVTSSSDGTARVWKNEINSTSTFRVLPHPSFVYTAKFHPATRELVVTGCYDSMIRIWKIDAREDAAILVRQLDVHKSFVNSICFDDEGHHMYSGDCIGVIVVWDTYVKVNDVQTSVRHWTINKEIKETEFRGVPISYLEVHPNGKRLLIHTKDSTLRIMDLRILAARKFVGAANYREKIHSTLTPCGTLLFSGSEDGIVYVWNPETGEQVAMYSDLPFKSTIRDISYHPLENMVAFCAFGQSEPILLYIYDFQVAQQEAEMLKRYSGTLPLPGIHQSEDALCTCPKLPQQGSFQIDEFVNTENSSSRKIQLVKQRLETVTEVIRSCAAKVNKNLSMTSPPPGPAKKPRVKQSFVLTTDEIIHQFGLPQTAFISIERGPFVRHVDPPPMVVALYDYTASRSDELTIHRGDIIRVYFKDNEDWWYGSVRKGQEGFFPANHVASETLYRDSPPKVKERSPPLTPKEKTKPEKPLASQKQSLSKGRPLDPRLGPQPVGHSEKGKDQNVEDRGHKVDMETKKSEPVVRKVTLIE

Tissue specificity:Expressed in the retina (at protein level) (PubMed:29899041). Highly expressed in the brain (PubMed:12186888, PubMed:15467982). Highly expressed in the testis (PubMed:12186888). Expressed in the kidney, thymus, heart, lung, spleen (PubMed:12186888). Weakly expressed in the liver, stomach, pancreas, and embryo (PubMed:12186888). Strongly expressed during periods of both cortical and cerebellar development (PubMed:15467982). {ECO:0000269|PubMed:12186888, ECO:0000269|PubMed:15467982, ECO:0000269|PubMed:29899041}.

Induction:

Developmental stage:First detected at 7 days post conception (dpc) and is also present at 11 dpc, 15 dpc and 17 dpc with the highest level at 15 dpc. Expression in whole brain is detected from 14 dpc to adult. Expression in cerebellum appears maximal at 18 dpc and postnatal days 5 (P5), whereas expression in cerebral cortex appears maximal at 16 dpc and 18 dpc. {ECO:0000269|PubMed:15467982}.

Protein families:


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