RETNB_MOUSE Q99P86
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UniProt:Q99P86
Recommended name:Resistin-like beta
EC number:
Alternative names:(Cysteine-rich secreted protein A12-beta) (Cysteine-rich secreted protein FIZZ2) (RELMbeta)
Cleaved into:
GeneID:57263
Gene names (primary ):Retnlb
Gene names (synonym ):Fizz2
Gene names (ORF ):
Length:105
Mass:11278
Sequence:MKPTLCFLFILVSLFPLIVPGNAQCSFESLVDQRIKEALSRQEPKTISCTSVTSSGRLASCPAGMVVTGCACGYGCGSWDIRNGNTCHCQCSVMDWASARCCRMA
Tissue specificity:Strongly expressed in colon, and at lower levels in ileum (PubMed:15834545). In colon, found throughout the crypt and surface epithelium and in goblet cells (at protein level) (PubMed:15834545). Specific to the gastrointestinal tract; not detected in other tissues tested (PubMed:11209052, PubMed:15834545). {ECO:0000269|PubMed:11209052, ECO:0000269|PubMed:15834545}.
Induction:Up-regulated in colon in response to a high-fat diet. Also up-regulated in obese mice mutant for the leptin receptor LEPR (db/db genotype). {ECO:0000269|PubMed:15834545}.
Developmental stage:
Protein families:Resistin/FIZZ family