K2C71_MOUSE   Q9R0H5


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UniProt:Q9R0H5

Recommended name:Keratin, type II cytoskeletal 71

EC number:

Alternative names:(Cytokeratin-6G) (CK-6G) (Cytokeratin-71) (CK-71) (Keratin-6G) (K6G) (Keratin-71) (K71) (Type II inner root sheath-specific keratin-K6irs1) (mK6irs) (mK6irs1/Krt2-6g) (Type-II keratin Kb34)

Cleaved into:

GeneID:56735

Gene names  (primary ):Krt71

Gene names  (synonym ):K6irs1 Kb34 Krt2-6g Krt6g

Gene names  (ORF ):

Length:524

Mass:57383

Sequence:MSRQFTCKSGASNRGFSGCSAVLSGGSSSSYRAGGKGLSGGFGSRSLYSLGGGRSITLNMASGSGKNGGFGFGRNRASGFAGSIFGSVALGPVCPAVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLQTKWELLQQLDLNNCKNNLEPILEGHISNMRKQLETLSGDRVRLDSELRNVRDVVEDYKKKYEEEINRRTAAENEFVLLKKDVDAAYANKVELQAKVDTMDQDIKFFKCLFEAEMAQIQSHISDMSVILSMDNNRNLDLDSIIDEVRAQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEITELTRFIQRLRSEIENAKKQASNLETAIADAEQRGDSALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEYSSPVSISIISSTSGSGGYGFRPSTVSGGYVANSTSCISGVCSVRGGENRSRGSASDYKDTLTKGSSLSTPSKKGGR

Tissue specificity:Specifically expressed in the inner root sheath (IRS) of the hair follicle. Present in Henle and the Huxley layers of the IRS, while expression in the cuticle is unsure (at protein level). {ECO:0000269|PubMed:11231308, ECO:0000269|PubMed:11703281, ECO:0000269|PubMed:14573483}.

Induction:

Developmental stage:Expressed exclusively in the inner root sheath (IRS) of anagen hair follicles, where expression is predominantly in the hair cone during anagen III and in the Huxley and Henle layers of the inner root sheath during anagen VI. {ECO:0000269|PubMed:11231308}.

Protein families:Intermediate filament family


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