8ODP_RAT   P53369


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UniProt:P53369

Recommended name:Oxidized purine nucleoside triphosphate hydrolase Curated

EC number:EC:3.6.1.56

Alternative names:2-hydroxy-dATP diphosphatase 7,8-dihydro-8-oxoguanine triphosphatase 8-oxo-dGTPase Methylated purine nucleoside triphosphate hydrolase By Similarity (EC:3.6.1.- By Similarity) . EC:3.6.1.- (UniProtKB | ENZYME | Rhea) By Similarity Nucleoside diphosphate-linked moiety X motif 1 (Nudix motif 1)

Cleaved into:

GeneID:117260

Gene names  (primary ):Nudt1

Gene names  (synonym ):Mth1

Gene names  (ORF ):

Length:156

Mass:18,018

Sequence:MSTSRLYTLVLVLQPQRVLLGMKKRGFGAGRWNGFGGKVQEGETIEDGAKRELLEESGLRVDTLHKVGHISFEFVGSPELMDVHIFSTDHVHGTPTESEEMRPQWFQLDQIPFADMWPDDSYWFPLLLQKKKFCGHFKFHGQDTILSYSLREVDEF

Tissue specificity:Expressed in liver in hepatocytes and weakly in Kupffer's cells. Expression detected in testes in primary and secondary spermatocytes and interstitial cells. High expression levels detected in the inner cortex of kidney, with lower levels detected in the tubules of the outer cortex, medulla, renal pelvis and glomeruli (at protein level). Expressed in heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. 2 s

Induction:

Developmental stage:

Protein families:


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