KHDR3_HUMAN   O75525


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UniProt:O75525

Recommended name:KH domain-containing, RNA-binding, signal transduction-associated protein 3

EC number:

Alternative names:(RNA-binding protein T-Star) (Sam68-like mammalian protein 2) (SLM-2) (Sam68-like phosphotyrosine protein)

Cleaved into:

GeneID:10656

Gene names  (primary ):KHDRBS3

Gene names  (synonym ):SALP SLM2

Gene names  (ORF ):

Length:346

Mass:38800

Sequence:MEEKYLPELMAEKDSLDPSFTHALRLVNQEIEKFQKGEGKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMSILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYNDEIRQAQLQELTYLNGGSENADVPVVRGKPTLRTRGVPAPAITRGRGGVTARPVGVVVPRGTPTPRGVLSTRGPVSRGRGLLTPRARGVPPTGYRPPPPPPTQETYGEYDYDDGYGTAYDEQSYDSYDNSYSTPAQSGADYYDYGHGLSEETYDSYGQEEWTNSRHKAPSARTAKGVYRDQPYGRY

Tissue specificity:Ubiquitous with higher expression in testis, skeletal muscle and brain. Expressed in the kidney only in podocytes, the glomerular epithelial cells of the kidney. Strongly expressed after meiosis. {ECO:0000269|PubMed:10077576, ECO:0000269|PubMed:10332027, ECO:0000269|PubMed:10564820}.

Induction:Induced in proteinuric diseases. Down-regulated in immortalized fibroblasts isolated after a proliferative crisis accompanied with massive cell death. {ECO:0000269|PubMed:11714634, ECO:0000269|PubMed:15901763}.

Developmental stage:

Protein families:KHDRBS family


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