CDK1_RAT   P39951


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UniProt:P39951

Recommended name:Cyclin-dependent kinase 1

EC number:EC:2.7.11.22

Alternative names:CDK1

Cleaved into:

GeneID:54237

Gene names  (primary ):Cdk1

Gene names  (synonym ):Cdc2, Cdc2a, Cdkn1

Gene names  (ORF ):

Length:297

Mass:34,135

Sequence:MEDYIKIEKIGEGTYGVVYKGRHRTTGQIVAMKKIRLESEEEGVPSTAIREISLLKELRHPNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQFMDSSLVKSYLYQILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLVYDPAKRISGKMALKHPYFDDLDNQIKKM

Tissue specificity:Follow a cyclic expression; during interphase, accumulates gradually following G1, S to reach a critical threshold at the end of G2, which promotes self-activation and triggers onset of mitosis. Induced transiently by TGFB1 at an early phase of TGFB1-mediated apoptosis. Expressed during S-phase in mitogen-stimulated hepatocytes. 2 s

Induction:

Developmental stage:

Protein families:


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