CHIP_RAT   A6HD62


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UniProt:A6HD62

Recommended name:E3 ubiquitin-protein ligase CHIP Curated

EC number:EC:2.3.2.27

Alternative names:Carboxy terminus of Hsp70-interacting protein By Similarity RING-type E3 ubiquitin transferase CHIP Curated STIP1 homology and U box-containing protein 1 Imported

Cleaved into:

GeneID:287155

Gene names  (primary ):Stub1

Gene names  (synonym ):Chip 1 Publication

Gene names  (ORF ):

Length:304

Mass:34,886

Sequence:MKGKEEKEGGARLGTGGGGSPDKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLTRLIAAERERELEECQRNHEGDEDDGHIRAQQACIEAKHDKYMADMNELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWVEDY

Tissue specificity:Expressed in the adventitia layer of the carotid artery (at protein level) (PubMed:19483080). Expressed in the CA1 region of the hippocampus (at protein level) (PubMed:21808025). Expressed in the uterus (at protein level) (PubMed:21808025). 2 s

Induction:Expressed in neurons at 18.5 dpc (at protein level). 1 Publication

Developmental stage:Induced by oxygen and glucose deprivation in neuronal cells (PubMed:29934347). Induced in the neointimal layer of the carotid artery by blood flow cessation injury (PubMed:19483080). 2 s

Protein families:


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