BAG1_HUMAN Q99933
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UniProt:Q99933
Recommended name:BAG family molecular chaperone regulator 1
EC number:
Alternative names:(BAG-1) (Bcl-2-associated athanogene 1)
Cleaved into:
GeneID:573
Gene names (primary ):BAG1
Gene names (synonym ):HAP
Gene names (ORF ):
Length:345
Mass:38779
Sequence:MAQRGGARRPRGDRERLGSRLRALRPGREPRQSEPPAQRGPPPSGRPPARSTASGHDRPTRGAAAGARRPRMKKKTRRRSTRSEELTRSEELTLSEEATWSEEATQSEEATQGEEMNRSQEVTRDEESTRSEEVTREEMAAAGLTVTVTHSNEKHDLHVTSQQGSSEPVVQDLAQVVEEVIGVPQSFQKLIFKGKSLKEMETPLSALGIQDGCRVMLIGKKNSPQEEVELKKLKHLEKSVEKIADQLEELNKELTGIQQGFLPKDLQAEALCKLDRRVKATIEQFMKILEEIDTLILPENFKDSRLKRKGLVKKVQAFLAECDTVEQNICQETERLQSTNFALAE
Tissue specificity:Isoform 4 is the most abundantly expressed isoform. It is ubiquitously expressed throughout most tissues, except the liver, colon, breast and uterine myometrium. Isoform 1 is expressed in the ovary and testis. Isoform 4 is expressed in several types of tumor cell lines, and at consistently high levels in leukemia and lymphoma cell lines. Isoform 1 is expressed in the prostate, breast and leukemia cell lines. Isoform 3 is the least abundant isoform in tumor cell lines (at protein level). {ECO:0000269|PubMed:9679980}.
Induction:Up-regulated during differentiation of bladder epithelial cells and down-regulated during differentiation of prostate epithelium. {ECO:0000269|PubMed:9679980}.
Developmental stage:
Protein families: