PTN_RAT P63090
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UniProt:P63090
Recommended name：Pleiotrophin 1 Publication
EC number：
Alternative names：Heparin-binding brain mitogen 1 Publication (HBBM 1 Publication) Heparin-binding growth factor 8 By Similarity (HBGF-8 By Similarity) Heparin-binding growth-associated molecule 1 Publication (HB-GAM 1 Publication) Heparin-binding neutrophic factor 1 Publication (HBNF 1 Publication) Osteoblast-specific factor 1 By Similarity (OSF-1 By Similarity)
Cleaved into：
GeneID：24924
Gene names (primary )：Ptn
Gene names (synonym )：
Gene names (ORF )：
Length：168
Mass：18,869
Sequence：MSSQQYQQQRRKFAAAFLALIFILAAVDTAEAGKKEKPEKKVKKSDCGEWQWSVCVPTSGDCGLGTREGTRTGAECKQTMKTQRCKIPCNWKKQFGAECKYQFQAWGECDLNTALKTRTGSLKRALHNADCQKTVTISKPCGKLTKPKPQAESKKKKKEGKKQEKMLD
Tissue specificity：Expressed in brain (PubMed:2170351). Hardly expressed in bone. Abundantly expressed in the growth plate. Intensely expressed in the cartilage matrix that forms the hollow for the secondary ossification center. Is expressed selectively by the osteocytes of the lamellar bone, whereas it is hardly expressed by those of the woven bone. Is detected in the matrix surrounding the osteocytes and in the canaliculi of the osteocytes. Is distributed on the surface of lamellar bone (PubMed:9817766). 2 s
Induction：
Developmental stage：Expressed at low levels in the brain in early embryonic stages. Levels increase to a maximum before or just after birth, and are lower in adult brain (PubMed:1768439). At 16 dpc intensely expressed in the matrix of the developing cartilage and persists in the matrix of the mineralized cartilage at 20 dpc (at protein level). Localized within the unmineralized cartilage matrix (at mRNA level) (PubMed:9817766). 2 s
Protein families：