RNFT1_HUMAN Q5M7Z0
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UniProt:Q5M7Z0
Recommended name：E3 ubiquitin-protein ligase RNFT1
EC number：EC:2.3.2.27
Alternative names：(Protein PTD016) (RING finger and transmembrane domain-containing protein 1)
Cleaved into：
GeneID：51136
Gene names (primary )：RNFT1
Gene names (synonym )：
Gene names (ORF )：PTD016
Length：435
Mass：49710
Sequence：MPLFLLSLPTPPSASGHERRQRPEAKTSGSEKKYLRAMQANRSQLHSPPGTGSSEDASTPQCVHTRLTGEGSCPHSGDVHIQINSIPKECAENASSRNIRSGVHSCAHGCVHSRLRGHSHSEARLTDDTAAESGDHGSSSFSEFRYLFKWLQKSLPYILILSVKLVMQHITGISLGIGLLTTFMYANKSIVNQVFLRERSSKIQCAWLLVFLAGSSVLLYYTFHSQSLYYSLIFLNPTLDHLSFWEVFWIVGITDFILKFFFMGLKCLILLVPSFIMPFKSKGYWYMLLEELCQYYRTFVPIPVWFRYLISYGEFGNVTRWSLGILLALLYLILKLLEFFGHLRTFRQVLRIFFTQPSYGVAASKRQCSDVDDICSICQAEFQKPILLICQHIFCEECMTLWFNREKTCPLCRTVISDHINKWKDGATSSHLQIY
Tissue specificity：Expressed at highest levels in testis, lower levels in heart, liver, lung, and kidney (PubMed:17074343). Not detected in brain, ovary, and uterus (PubMed:17074343). Down-regulated in testis from patients with maturation arrest (MA) or Sertoli cell-only syndrome (SCOS) (PubMed:17074343). Ubiquitously expressed with high expression in testis (PubMed:27485036). {ECO:0000269|PubMed:17074343, ECO:0000269|PubMed:27485036}.
Induction：Up-regulated by endoplasmic reticulum (ER) stress triggered by thapsigargin or tunicamycin. {ECO:0000269|PubMed:27485036}.
Developmental stage：
Protein families：