KAPCA_HUMAN   P17612


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UniProt:P17612

Recommended name:cAMP-dependent protein kinase catalytic subunit alpha

EC number:EC:2.7.11.11

Alternative names:(PKA C-alpha)

Cleaved into:

GeneID:5566

Gene names  (primary ):PRKACA

Gene names  (synonym ):PKACA

Gene names  (ORF ):

Length:351

Mass:40590

Sequence:MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF

Tissue specificity:Isoform 1 is ubiquitous. Isoform 2 is sperm-specific and is enriched in pachytene spermatocytes but is not detected in round spermatids. {ECO:0000269|PubMed:10906071, ECO:0000269|PubMed:21812984}.

Induction:

Developmental stage:

Protein families:Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily


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