ALKB5_MOUSE   Q3TSG4


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UniProt:Q3TSG4

Recommended name:RNA demethylase ALKBH5

EC number:EC 1.14.11.-

Alternative names:(Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)

Cleaved into:

GeneID:268420

Gene names  (primary ):Alkbh5

Gene names  (synonym ):Abh5 Ofoxd

Gene names  (ORF ):

Length:395

Mass:44411

Sequence:MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPASGTTKRKYQEDSDPERSDYEEHQLQKEEEARKVKSGIRQIRLFSQDECSKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPDWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSTLPPSYASDRLSGNTRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCPEAASSPTRKVKMRRH

Tissue specificity:Widely expressed, with highest expression in testis (PubMed:23177736). In testis, present in almost all testicular cell types except elongating and elongated spermatids (at protein level) (PubMed:29279410). Among spermatogenic cells, present at high level in spermatocytes; medium levels in spermatogonia and lower levels in round spermatids (at protein level) (PubMed:29279410). {ECO:0000269|PubMed:23177736, ECO:0000269|PubMed:29279410}.

Induction:

Developmental stage:

Protein families:AlkB family


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