ALKB5_MOUSE Q3TSG4
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UniProt:Q3TSG4
Recommended name:RNA demethylase ALKBH5
EC number:EC 1.14.11.-
Alternative names:(Alkylated DNA repair protein alkB homolog 5) (Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5)
Cleaved into:
GeneID:268420
Gene names (primary ):Alkbh5
Gene names (synonym ):Abh5 Ofoxd
Gene names (ORF ):
Length:395
Mass:44411
Sequence:MAAASGYTDLREKLKSMTSRDNYKAGSREAAAAAAAAVAAAAAAAAAAEPYPASGTTKRKYQEDSDPERSDYEEHQLQKEEEARKVKSGIRQIRLFSQDECSKIEARIDEVVSRAEKGLYNEHTVDRAPLRNKYFFGEGYTYGAQLQKRGPGQERLYPPGDVDEIPDWVHQLVIQKLVEHRVIPEGFVNSAVINDYQPGGCIVSHVDPIHIFERPIVSVSFFSDSALCFGCKFQFKPIRVSEPVLSLPVRRGSVTVLSGYAADEITHCIRPQDIKERRAVIILRKTRLDAPRLETKSLSSSTLPPSYASDRLSGNTRDPALKPKRSHRKADPDAAHRPRILEMDKEENRRSVLLPTHRRRGSFSSENYWRKSYESSEDCPEAASSPTRKVKMRRH
Tissue specificity:Widely expressed, with highest expression in testis (PubMed:23177736). In testis, present in almost all testicular cell types except elongating and elongated spermatids (at protein level) (PubMed:29279410). Among spermatogenic cells, present at high level in spermatocytes; medium levels in spermatogonia and lower levels in round spermatids (at protein level) (PubMed:29279410). {ECO:0000269|PubMed:23177736, ECO:0000269|PubMed:29279410}.
Induction:
Developmental stage:
Protein families:AlkB family