PGTB2_MOUSE P53612
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UniProt:P53612
Recommended name:Geranylgeranyl transferase type-2 subunit beta
EC number:EC 2.5.1.60
Alternative names:(Geranylgeranyl transferase type II subunit beta) (GGTase-II-beta) (Rab geranyl-geranyltransferase subunit beta) (Rab GG transferase beta) (Rab GGTase beta) (Rab geranylgeranyltransferase subunit beta) (Type II protein geranyl-geranyltransferase subunit beta)
Cleaved into:
GeneID:19352
Gene names (primary ):Rabggtb
Gene names (synonym ):
Gene names (ORF ):
Length:339
Mass:37803
Sequence:MGSLLFSWKGTQQKDVTIKSDAPDTLLLEKHADYIASYGSKKDDYEYCMSEYLRMSGVYWGLTVMDLMGQLHRMNREEILVFIKSCQHECGGISASIGHDPHLLYTLSAVQILTLYDSVHVINVDKVVAYVQSLQKEDGSFAGDIWGEIDTRFSFCAVATLALLGKLDAINVEKAIEFVLSCMNFDGGFGCRPGSESHAGQIYCCTGFLAITSQLHQVNSDLLGWWLCERQLPSGGLNGRPEKLPDVCYSWWVLASLKIIGRLHWIDREKLRSFILACQDEETGGFADRPGDMVDPFHTLFGIAGLSLLGEEQIKPVSPVFCMPEEVLQRVNVQPELVS
Tissue specificity:Ubiquitous. Detected in all the major organs in adult animals. {ECO:0000269|PubMed:9031634}.
Induction:Increased dramatically by cycloheximide (CHX) treatment within a short time (as early as 2 hours). Actinomycin D was used to determine the half-life, CHX treatment resulted in a dramatic increase of the half-life from 8 hours to greater than 12 hours. {ECO:0000269|PubMed:9031634}.
Developmental stage:Specific expression was elevated in mid-gestation stages, particularly developing liver and spinal cord. {ECO:0000269|PubMed:9031634}.
Protein families:Protein prenyltransferase subunit beta family