RIR2B_HUMAN Q7LG56
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UniProt:Q7LG56
Recommended name：Ribonucleoside-diphosphate reductase subunit M2 B
EC number：EC:1.17.4.1
Alternative names：(TP53-inducible ribonucleotide reductase M2 B) (p53-inducible ribonucleotide reductase small subunit 2-like protein) (p53R2)
Cleaved into：
GeneID：50484
Gene names (primary )：RRM2B
Gene names (synonym )：P53R2
Gene names (ORF )：
Length：351
Mass：40737
Sequence：MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
Tissue specificity：Widely expressed at a high level in skeletal muscle and at a weak level in thymus. Expressed in epithelial dysplasias and squamous cell carcinoma. {ECO:0000269|PubMed:14583450}.
Induction：In response to DNA damage in a wild-type p53/TP53-dependent manner. {ECO:0000269|PubMed:10716435}.
Developmental stage：
Protein families：Ribonucleoside diphosphate reductase small chain family