PTK6_MOUSE Q64434
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UniProt:Q64434
Recommended name：Protein-tyrosine kinase 6
EC number：EC 2.7.10.2
Alternative names：(SRC-related intestinal kinase)
Cleaved into：
GeneID：20459
Gene names (primary )：Ptk6
Gene names (synonym )：Sik
Gene names (ORF )：
Length：451
Mass：51972
Sequence：MVSWDKAHLGPKYVGLWDFKARTDEELSFQAGDLLHVTKKEELWWWATLLDAEGKALAEGYVPHNYLAEKETVESEPWFFGCISRSEAMHRLQAEDNSKGAFLIRVSQKPGADYVLSVRDAQAVRHYRIWKNNEGRLHLNEAVSFSNLSELVDYHKTQSLSHGLQLSMPCWKHKTEPLPHWDDWERPREEFTLCKKLGAGYFGEVFEALWKGQVHVAVKVISRDNLLHQHTFQAEIQAMKKLRHKHILSLYAVATAGDPVYIITELMPKGNLLQLLRDSDEKALPILELVDFASQVAEGMCYLESQNYIHRDLAARNVLVTENNLCKVGDFGLARLVKEDIYLSHEHNVPYKWTAPEALSRGHYSIKSDVWSFGVLLHEIFSRGQMPYPGMSNHETFLRVDAGYRMPCPLECPPNIHKLMLSCWSRDPKQRPCFKDLCEKLTGITRYENLV
Tissue specificity：Expressed only in epithelial tissues, including the skin and lining of the alimentary canal. Restricted to the cell layers immediately above the proliferative cell zone in these epithelia. {ECO:0000269|PubMed:15471878}.
Induction：
Developmental stage：First detected at day 15.5 of gestation in the embryo, where it is expressed in the newly forming granular layer of the skin. Is found in stomach at day 17.5. {ECO:0000269|PubMed:10430081}.
Protein families：Protein kinase superfamily, Tyr protein kinase family, BRK/PTK6/SIK subfamily