SIT1_HUMAN Q9Y3P8
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UniProt:Q9Y3P8
Recommended name:Signaling threshold-regulating transmembrane adapter 1
EC number:
Alternative names:(SHP2-interacting transmembrane adapter protein) (Suppression-inducing transmembrane adapter 1) (gp30/40)
Cleaved into:
GeneID:27240
Gene names (primary ):SIT1
Gene names (synonym ):SIT
Gene names (ORF ):
Length:196
Mass:21126
Sequence:MNQADPRLRAVCLWTLTSAAMSRGDNCTDLLALGIPSITQAWGLWVLLGAVTLLFLISLAAHLSQWTRGRSRSHPGQGRSGESVEEVPLYGNLHYLQTGRLSQDPEPDQQDPTLGGPARAAEEVMCYTSLQLRPPQGRIPGPGTPVKYSEVVLDSEPKSQASGPEPELYASVCAQTRRARASFPDQAYANSQPAAS
Tissue specificity:Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma. {ECO:0000269|PubMed:10209036, ECO:0000269|PubMed:16160011}.
Induction:
Developmental stage:
Protein families: