ENOA_MOUSE P17182
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UniProt:P17182
Recommended name：Alpha-enolase
EC number：EC 4.2.1.11
Alternative names：(2-phospho-D-glycerate hydro-lyase) (Enolase 1) (Non-neural enolase) (NNE)
Cleaved into：
GeneID：13806
Gene names (primary )：Eno1
Gene names (synonym )：Eno-1
Gene names (ORF )：
Length：434
Mass：47141
Sequence：MSILRIHAREIFDSRGNPTVEVDLYTAKGLFRAAVPSGASTGIYEALELRDNDKTRFMGKGVSQAVEHINKTIAPALVSKKVNVVEQEKIDKLMIEMDGTENKSKFGANAILGVSLAVCKAGAVEKGVPLYRHIADLAGNPEVILPVPAFNVINGGSHAGNKLAMQEFMILPVGASSFREAMRIGAEVYHNLKNVIKEKYGKDATNVGDEGGFAPNILENKEALELLKTAIAKAGYTDQVVIGMDVAASEFYRSGKYDLDFKSPDDPSRYITPDQLADLYKSFVQNYPVVSIEDPFDQDDWGAWQKFTASAGIQVVGDDLTVTNPKRIAKAASEKSCNCLLLKVNQIGSVTESLQACKLAQSNGWGVMVSHRSGETEDTFIADLVVGLCTGQIKTGAPCRSERLAKYNQILRIEEELGSKAKFAGRSFRNPLAK
Tissue specificity：Testis. Found in the principal piece of sperm tail (at protein level). The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. In striated muscle, expression of ENO1 appears to be independent of fiber type. {ECO:0000269|PubMed:11229603, ECO:0000269|PubMed:23446454}.
Induction：
Developmental stage：During ontogenesis, there is a transition from the alpha/alpha homodimer to the alpha/beta heterodimer in striated muscle cells, and to the alpha/gamma heterodimer in nerve cells. In embryonic muscle, ENO1 is highly expressed until 17 dpc. Decreased levels from P5. {ECO:0000269|PubMed:9169614}.
Protein families：Enolase family