PTHD1_MOUSE Q14B62
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UniProt:Q14B62
Recommended name：Patched domain-containing protein 1
EC number：
Alternative names：
Cleaved into：
GeneID：211612
Gene names (primary )：ptchd1
Gene names (synonym )：
Gene names (ORF )：
Length：888
Mass：101506
Sequence：MLRQVLHRGLRTCFSRLGHFIASHPVFFASAPVLISILLGASFSRYQVEESVEHLLAPQHSLAKIERNLVNSLFPVNRSKHRLYSDLQTPGRYGRVIVTSYQKANMLDQHHTDLILKLHTAVTKIQVPRPGFNYTFAHICVLNNDKTCIVDDIVHVLEELKNARATNRTNFAITYPITHLKDGRAVYNGHQLGGVTVHSKDRVKSAEAIQLTYYLQSINSLNDMVAERWESSFCDTVKLFQKSNSKVKIYPYTSSSLREDFQKTSRVSERYLVTSLILVVTMAILCCSMQDCVRSKPWLGLLGLVTISLATLTAAGIINLTGGKYNSTFLGVPFVMLGHGLYGTFEMLSSWRKTREDQHVKERTAEVYADSMLSFSLTTAMYLVTFGIGASPFTNIEAARIFCCNSCIAILFNYLYVLSFYGSSLVFTGYIENNYQHSIFCRKVPKPDVLQEKPAWYRFLLTARFSEETAEGEEANTYESHLLVCFLKRYYCDWITNTYVKPFVVLFYLIYISFALMGYLQVSEGSDLSNIVATATQTIEYTTAHQKYFNNYSPVIGFYIYESIEYWNSSVQEDVLEYTKGFVRISWFESYLNYLRKLNVSTDLPKKNFTDMLRNSFLKTPQFSHFQEDIIFSKKYNDEVDVVASRMFLVAKTMETNREELYDLLETLRRLSVTSKVKFIVFNPSFVYMDRYASSLGAPLHNSCISALFLLFFSAFLVADSLINVWITLTVVSVEFGVIGFMTLWKVELDCISVLCLIYGINYTIDNCAPLLSTFVLGKDFTRTKWVKNALEVHGVAILQSYLCYIVGLFPLAAVPSNLTCTLFRCLFLIAFVTFFHCFAILPVILTFLPPSKKKRKEKKNPENREEIECVEMVDIDSTRVVDQITTV
Tissue specificity：Broadly expressed in the brain (PubMed:20844286). Selectively expressed in the thalamic reticular nucleus (TRN) in early development and continues to be enriched in this structure throughout adult life (PubMed:27007844). {ECO:0000269|PubMed:20844286, ECO:0000269|PubMed:27007844}.
Induction：
Developmental stage：Widely expressed in the developing brain from 9.5 day post coitum (dpc) to postnatal day 1 (P1) (PubMed:20844286). Specifically expressed in the thalamic reticular nucleus (TRN) at birth. Expressed in the striatum, cortex and cerebellum by P15 onwards (PubMed:27007844). {ECO:0000269|PubMed:20844286, ECO:0000269|PubMed:27007844}.
Protein families：Patched family