B2L11_HUMAN O43521
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UniProt:O43521
Recommended name：Bcl-2-like protein 11
EC number：
Alternative names：(Bcl2-L-11) (Bcl2-interacting mediator of cell death)
Cleaved into：
GeneID：10018
Gene names (primary )：BCL2L11
Gene names (synonym )：BIM
Gene names (ORF )：
Length：198
Mass：22171
Sequence：MAKQPSDVSSECDREGRQLQPAERPPQLRPGAPTSLQTEPQGNPEGNHGGEGDSCPHGSPQGPLAPPASPGPFATRSPLFIFMRRSSLLSRSSSGYFSFDTDRSPAPMSCDKSTQTPSPPCQAFNHYLSAMASMRQAEPADMRPEIWIAQELRRIGDEFNAYYARRVFLNNYQAAEDHPRMVILRLLRYIVRLVWRMH
Tissue specificity：Isoform BimEL, isoform BimL and isoform BimS are the predominant isoforms and are widely expressed with tissue-specific variation. Isoform Bim-gamma is most abundantly expressed in small intestine and colon, and in lower levels in spleen, prostate, testis, heart, liver and kidney. {ECO:0000269|PubMed:12019181}.
Induction：By ER stress in a DDIT3/CHOP-dependent manner. {ECO:0000269|PubMed:22761832}.
Developmental stage：
Protein families：Bcl-2 family