ERG24_HUMAN   O76062


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UniProt:O76062

Recommended name:Delta(14)-sterol reductase TM7SF2

EC number:EC:1.3.1.70

Alternative names:(3-beta-hydroxysterol Delta(14)-reductase) (Another new gene 1 protein) (C-14 sterol reductase) (C14SR) (Putative sterol reductase SR-1) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2)

Cleaved into:

GeneID:7108

Gene names  (primary ):TM7SF2

Gene names  (synonym ):ANG1

Gene names  (ORF ):

Length:418

Mass:46406

Sequence:MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY

Tissue specificity:Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. {ECO:0000269|PubMed:16784888, ECO:0000269|PubMed:9878250}.

Induction:By sterol starvation. {ECO:0000269|PubMed:16784888, ECO:0000269|PubMed:27336722}.

Developmental stage:

Protein families:ERG4/ERG24 family


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