ERG24_HUMAN O76062
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UniProt:O76062
Recommended name:Delta(14)-sterol reductase TM7SF2
EC number:EC:1.3.1.70
Alternative names:(3-beta-hydroxysterol Delta(14)-reductase) (Another new gene 1 protein) (C-14 sterol reductase) (C14SR) (Putative sterol reductase SR-1) (Sterol C14-reductase) (Transmembrane 7 superfamily member 2)
Cleaved into:
GeneID:7108
Gene names (primary ):TM7SF2
Gene names (synonym ):ANG1
Gene names (ORF ):
Length:418
Mass:46406
Sequence:MAPTQGPRAPLEFGGPLGAAALLLLLPATMFHLLLAARSGPARLLGPPASLPGLEVLWSPRALLLWLAWLGLQAALYLLPARKVAEGQELKDKSRLRYPINGFQALVLTALLVGLGMSAGLPLGALPEMLLPLAFVATLTAFIFSLFLYMKAQVAPVSALAPGGNSGNPIYDFFLGRELNPRICFFDFKYFCELRPGLIGWVLINLALLMKEAELRGSPSLAMWLVNGFQLLYVGDALWHEEAVLTTMDITHDGFGFMLAFGDMAWVPFTYSLQAQFLLHHPQPLGLPMASVICLINATGYYIFRGANSQKNTFRKNPSDPRVAGLETISTATGRKLLVSGWWGMVRHPNYLGDLIMALAWSLPCGVSHLLPYFYLLYFTALLVHREARDERQCLQKYGLAWQEYCRRVPYRIMPYIY
Tissue specificity:Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, testis and adrenal gland, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes. {ECO:0000269|PubMed:16784888, ECO:0000269|PubMed:9878250}.
Induction:By sterol starvation. {ECO:0000269|PubMed:16784888, ECO:0000269|PubMed:27336722}.
Developmental stage:
Protein families:ERG4/ERG24 family