PSB5_HUMAN   P28074


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UniProt:P28074

Recommended name:Proteasome subunit beta type-5

EC number:EC:3.4.25.1

Alternative names:(Macropain epsilon chain) (Multicatalytic endopeptidase complex epsilon chain) (Proteasome chain 6) (Proteasome epsilon chain) (Proteasome subunit MB1) (Proteasome subunit X)

Cleaved into:

GeneID:5693

Gene names  (primary ):PSMB5

Gene names  (synonym ):LMPX MB1 X

Gene names  (ORF ):

Length:263

Mass:28480

Sequence:MALASVLERPLPVNQRGFFGLGGRADLLDLGPGSLSDGLSLAAPGWGVPEEPGIEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKRGPGLYYVDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGAVNLYHVREDGWIRVSSDNVADLHEKYSGSTP

Tissue specificity:

Induction:Down-regulated by IFNG/IFN-gamma (at protein level). Induced in breast cancer tissue. Up-regulated by sulforaphane in breast cancer cells. {ECO:0000269|PubMed:17004105, ECO:0000269|PubMed:18602823, ECO:0000269|PubMed:8066462, ECO:0000269|PubMed:8663318}.

Developmental stage:

Protein families:Peptidase T1B family


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