CEAM1_HUMAN P13688
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UniProt:P13688
Recommended name:Carcinoembryonic antigen-related cell adhesion molecule 1
EC number:
Alternative names:(Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)
Cleaved into:
GeneID:634
Gene names (primary ):CEACAM1
Gene names (synonym ):BGP BGP1
Gene names (ORF ):
Length:526
Mass:57560
Sequence:MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ
Tissue specificity:Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). The predominant forms expressed by T cells are those containing a long cytoplasmic domain (PubMed:18424730). Expressed in granulocytes and lymphocytes. Leukocytes only express isoforms 6 and isoform 1 (PubMed:11994468). {ECO:0000269|PubMed:10436421, ECO:0000269|PubMed:11994468, ECO:0000269|PubMed:18424730}.
Induction:Induced in primary T cells by activation with IL-2. {ECO:0000269|PubMed:18424730}.
Developmental stage:
Protein families:Immunoglobulin superfamily, CEA family