CEAM1_HUMAN   P13688


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UniProt:P13688

Recommended name:Carcinoembryonic antigen-related cell adhesion molecule 1

EC number:

Alternative names:(Biliary glycoprotein 1) (BGP-1) (CD antigen CD66a)

Cleaved into:

GeneID:634

Gene names  (primary ):CEACAM1

Gene names  (synonym ):BGP BGP1

Gene names  (ORF ):

Length:526

Mass:57560

Sequence:MGHLSAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFGYSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALIAVALACFLHFGKTGRASDQRDLTEHKPSVSNHTQDHSNDPPNKMNEVTYSTLNFEAQQPTQPTSASPSLTATEIIYSEVKKQ

Tissue specificity:Expressed in columnar epithelial cells of the colon (at protein level) (PubMed:10436421). The predominant forms expressed by T cells are those containing a long cytoplasmic domain (PubMed:18424730). Expressed in granulocytes and lymphocytes. Leukocytes only express isoforms 6 and isoform 1 (PubMed:11994468). {ECO:0000269|PubMed:10436421, ECO:0000269|PubMed:11994468, ECO:0000269|PubMed:18424730}.

Induction:Induced in primary T cells by activation with IL-2. {ECO:0000269|PubMed:18424730}.

Developmental stage:

Protein families:Immunoglobulin superfamily, CEA family


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