CP131_MOUSE   Q62036


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UniProt:Q62036

Recommended name:Centrosomal protein of 131 kDa

EC number:

Alternative names:(5-azacytidine-induced protein 1) (Pre-acrosome localization protein 1)

Cleaved into:

GeneID:12009

Gene names  (primary ):Cep131

Gene names  (synonym ):Az1 Azi Azi1

Gene names  (ORF ):

Length:1060

Mass:120313

Sequence:MKGSRTITATPEGSPEAVDLSLIGLPPPMSQRPGSASATRSIFRSMSVATGSEPRKKALEATGPGGPRAINNLRRSNSTTQVNQSWTGSPRPAEPTDFLMLFEGSTSGRRRVASLSKASSEKEATWNVLDEQPRGLALPASAQSPSTLDSALGPRRKECPLAPSFTANNRSNKGAVGNCVTTMVHNHYASSKMVSPPKSSNQTAPSLNNIVKAAAREGGEGSDLGKPRKNLSSASQSARGTTGLLRRREVTEEEAERFIHQVNQAAVTIQRWYRCQVQRRRAGAAALEHLLASKREGQRQRLGGGNLLELHRQEEAARKKAREEKARQARQAAIQVLQQKRAQKASEAEHRRPKDRPETRAPEQPRPMQEPGCVTHPKANNAGASIYPTGPADPCPPASESSPEQWQSPEDKPQDIHSQGEARQDLAVSGSSRGKARARATLDDLLDTLKLLEEEPEPLPHPKAYHKDRYAWTDEEEDANSLTADNLEKFGKLSAAPGPPDDGTLLSEAKLQSIMTFLDEMEKSGQERPAPWRESLVLEAGSGSEGSTSVMRLKLELEEKKQAMALLQRALAQQRDLTVRRVKETEKELTRQLRQQKEQYEATIQRHLSFIDQLIEDKKVLSEKCEAVVAELKHGDQRCRERVAQMQEQHELEIKKLKELMSATEKIRREKWINEKTKKIKEITVRGLEPEIQKLIAKHKQEVRRLRGLHEAELQQREEQAAQRHLRQAEELRQHLDREREVLGQQERERAQQRFEQHLEQEQRALEQQRRRLYNEVAEEKERLGQQAARQRAELEELRQQLEESSAALTRALRAEFERSREEQERRHQMELKALKDQLEAERQAWVASCAKKEEAWLLTRERELKEEIRKGRDQEIELVIHRLEADMTLAKEESERAAESRVKRVRDKYETELSELEQSERKLQERCSELKGRLGEAEGEKERLQSLVRQKEKELEDLRAVNTQMCSERASLAQVVRQEFAEQLAASQEETQRVKVELAELQARQQVELDEVHRRVKTALARKEAAVNSLRKQHEAAVKRADHLEELLEQHKGSSLSSK

Tissue specificity:Localized to the pre-acrosome region of round and elongated spermatids in testis but also present in ovary, brain and adipose tissue. {ECO:0000269|PubMed:8529672}.

Induction:By 5-azacytidine.

Developmental stage:Widely expressed during development, with strong expression in tissues with high levels of cilia-dependent developmental signaling such as the limbs, eyes, somite derivatives and brain. Significant amounts are found in the testis of 16 day old mice, at a late stage of pachytene spermatocytes when meiosis occurs. The level increases thereafter. {ECO:0000269|PubMed:24415959}.

Protein families:CEP131 family